Indocyanine Green Angiography Findings in Central Serous Chorioretinopathy

Background and objectives: To study the abnormalities in the choroidal circulation in cases of central serous chorioretinopathy (CSC) and to compare it with fundus fluorescein angiography. Setting and Design: Prospective, interventional and non comparative case series in a tertiary eye care institute. Material and Methods: 40 consecutive cases of CSC were included in the study. A complete clinical ophthalmological examination was performed. Simultaneous fluorescein angiography (FA) and indocyanine green angiography (ICGA) were done using confocal scanning laser ophthalmoscope and the digital images were analyzed. Results: FA showed leakage at the level of retinal pigment epithelium in all the cases (η=40, 100%) of CSC. Surrounding these leakage points, ICGA demonstrated choroidal filling delay (η=31, 77.5%), abnormal choroidal hyperfluorescence (η=34, 85%), venous dilatation (η=24, 60%) and persistent small localized hypofluorescence (η=28, 70%). Conclusion: Abnormality of the choroidal circulation in the form of regional vascular hyperpermeability was observed in CSC, which might be attributed to the disease pathogenesis.